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作者介绍门诊长期使用胺碘酮预防房颤发作的经验,观察250例(男、女例数相等),年龄35～75岁,65%<60岁。基础疾病:心肌营养不良81例(与糖尿病、肥胖症、更年期、饮酒等有关);冠心病71例:Ⅱ期高血压病55例;风湿性心脏病35例;心肌炎性心硬化8例。房颤发作史6月～15年,在每天、每周或每月经常发作占80%,间隔3～4月发作者10.4%,间隔6月发作者9.6%。胺碘酮剂量600(mg/日,分二次口服;年龄>70岁、或窦性心律心率60～55次/min、或Ⅰ度房室传导阻滞者,剂量减至400(mg/日。用药7～10天后房颤发作减
The author describes the out-patient long-term use of amiodarone to prevent the onset of atrial fibrillation, observed 250 cases (male and female cases equal), aged 35 to 75 years, 65% <60 years old. Basic diseases: Myocardial malnutrition in 81 cases (with diabetes, obesity, menopause, alcohol consumption, etc.); coronary heart disease in 71 cases: 55 cases of type II hypertension; rheumatic heart disease in 35 cases; myocardial inflammatory cardiomyopathy in 8 cases. Atrial fibrillation history of onset of June to 15 years, every day, every week or every month, 80% of the seizures, intervals of 3 to 4 months, 10.4% of the seizures, intervals in June, 9.6%. Amiodarone dose 600 (mg / day, divided into two orally; age> 70 years, or sinus rhythm of heart rate 60 ~ 55 times / min, or Ⅰ degree atrioventricular block, the dose was reduced to 400 (mg / day Atrial fibrillation after treatment 7 to 10 days reduced