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龋病是菌斑和其它因素共同作用下形成的。菌斑在发病中的作用和地位已受到有关学者的重视。国外有报导认为,菌斑内细菌种类和含量不同,决定了它们致龋能力的差异。由于口腔环境复杂,影响菌斑致龋因素很多,研究困难,故对不同人群口腔牙菌斑致龋能力还缺乏全面了解。一些学者从菌斑内细菌分离,菌斑产酸,菌斑pH变化和菌斑其它代谢活动来阐明菌斑在发病中的地位和作用,提出了许多值得重视的问题。利用菌斑中分离菌观察产酸和脱钙已有报导,由于难以模仿菌斑生态环境和不能实现各种细菌间的相互作用,故难于
Caries is plaque and other factors formed under the joint action. Plaque in the pathogenesis of the role and status of the scholars have been the attention. Foreign reports have suggested that different bacterial species and content of plaque determine their differences in cariogenic ability. Due to the complex oral environment, affecting a lot of dental plaque caries factors, the study is difficult, so different groups of dental plaque cariogenic ability is still lack of a comprehensive understanding. Some scholars have put forward many problems worthy of attention from the bacterial plaque separation, acid production of plaque, pH change of plaque and other metabolic activities of plaque to clarify the status and role of plaque in the pathogenesis. It has been reported that the production of acid and decalcification using the isolates in the plaque has been reported as difficult to mimic the plaque ecological environment and the inability to achieve the interaction between various bacteria