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采用１２月龄老年大白鼠３２只，随机分为四组，每组８只，用药组喂服无名异冲剂拌混饲料，对照组喂服一般饲料，１８月龄时处死，检测股骨中段弯曲破坏载荷及股骨皮质厚度。结果显示：雄性、雌性大白鼠用药组弯曲破坏载荷，平均骨皮质厚度明显高于对照组（＜０．０５～０．０１）；用药组、对照组雄性大白鼠弯曲破坏载荷明显高于雌性大白鼠（Ｐ＜０．０１）．表明：无名异冲剂具有预防和延缓骨质疏松的发生和发展作用；相同月龄中，雌性大白鼠骨质丧失相对地较雄性大白鼠明显。
Thirty-two 12-month-old rats were randomly divided into four groups of 8 in each. The medication group was fed with the unnamed iso-granules mixed feed. The control group was fed the general feed and was sacrificed at 18 months of age to test the bending of the middle of the femur. Load and femoral cortical thickness. The results showed that the bending load of the male and female rat drug group was significantly higher than that of the control group (<0.05-0.01). The bending damage load of the male and female rats in the drug and control groups was significantly higher than that of the female. White rats (P<0.01). The results showed that: “Wan Ming Yi Granules” has the effect of preventing and delaying the occurrence and development of osteoporosis. In the same month of age, the loss of bone mass of female rats is relatively more obvious than that of male rats.