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有关镉锭联合毒性研究国外报道较多,但由于实验方法、受试动物的不同,结果不尽一致,国内尚未见这方面的报道。为此,我们对镉锌联合致畸性进行了研究。 一、实验方法: 大鼠致畸试验采用武汉医学院方法(1)。孕鼠六组,每组15只。剂量分组见表1。除第Ⅴ组(a)受孕0天~15天经口染毒外,其余各组均于孕6~15
There are many reports about the combined toxicity of cadmium and cadmium in foreign countries, but due to the difference of experimental methods and animals tested, the results are not consistent and there is no such report yet in China. To this end, we conducted a joint study of teratogenicity of cadmium and zinc. First, the experimental method: Teratogenicity test using Wuhan Medical College method (1). Six pregnant rats, 15 rats in each group. Table 1 dose groups. Except group Ⅴ (a) constipation 0 to 15 days after oral administration, the other groups were pregnant 6 ~ 15