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目的:了解血压干预对妊娠期高血压患者尿微量白蛋白排泄率及孕妇和胎儿预后的影响。方法:88例患者随机分为治疗组47例以硝苯地平控释片干预血压,对照组41例不予血压干预;在入院时、产后24 h、产后42天做尿微量白蛋白排泄率、白昼血压与夜晚血压监测和新生儿1 min Apgar评分。结果:入院时,两组在尿微量白蛋白排泄率、白昼血压与夜晚血压差异无统计学意义(P>0.05),而产后24 h、产后42天两组差异均有统计学意义(P<0.01),且新生儿1 min Apgar评分两组差异有统计学意义(P<0.01)。结论:血压干预可获得良好的血压控制,产妇尿微量白蛋白排泄率良好及新生儿1分钟Apgar评分良好得益于良好的血压控制。
Objective: To understand the effect of blood pressure on urinary albumin excretion rate and prognosis of pregnant women and fetus in patients with gestational hypertension. Methods: A total of 88 patients were randomly divided into treatment group (n = 47) and nifedipine controlled release tablet (n = 41). No blood pressure intervention was given in the control group. Urinary albumin excretion rate was measured at 24 h postpartum, Daytime blood pressure and nighttime blood pressure monitoring and 1 min Apgar score in neonates. Results: At admission, there was no significant difference in urinary albumin excretion rate, daytime blood pressure and nighttime blood pressure between the two groups (P> 0.05), but there was significant difference between the two groups in postpartum 24 h and postnatal day 42 (P < 0.01). Neonat 1 minute Apgar score had significant difference between the two groups (P <0.01). CONCLUSIONS: Blood pressure intervention achieved good blood pressure control with good urinary albumin excretion rate and favorable neonatal 1-minute Apgar scores due to good blood pressure control.