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目的通过调查多药耐药菌(MDRO)的分布与流行特点,为有效降低MDRO医院感染提供临床依据。方法干预前资料来自回顾性收集2015年MDRO数据;干预后资料为采用目标性监测后2016年MDRO监测资料,对比评价防控及干预措施落实效果;资料采用SPSS 16.0软件进行统计分析。结果 MDRO发现率由2015年的0.3%降至2016年0.25%,医院MDRO感染率由2015年的0.15%降至2016年0.11%,差异有统计学意义(P<0.05);目标性监测期间隔离医嘱、隔离标识、医疗废物处理、宣教等较2015年改善显著,防控措施落实有效(P<0.05)。结论掌握MDRO的耐药特点及分布,加强防控措施的监管,查找防控薄弱环节,是有效预防或降低MDRO医院感染的关键;抗菌药物合理应用是下一步目标性监测督导重点。
Objective To investigate the distribution and epidemic characteristics of multi-drug resistant bacteria (MDRO) in order to provide a clinical basis for effectively reducing MDRO nosocomial infections. Methods The data before intervention were collected retrospectively from the 2015 MDRO data. The data after intervention were used to monitor the data of 2016 MDRO after target monitoring, and the effect of prevention and control and intervention measures was compared and evaluated. The data were analyzed by SPSS 16.0 software. Results The MDRO detection rate decreased from 0.3% in 2015 to 0.25% in 2016, and the MDRO infection rate in the hospital dropped from 0.15% in 2015 to 0.11% in 2016 (P <0.05). During the target monitoring interval Medical orders, isolation signs, medical waste treatment and mission education improved significantly from 2015, and effective prevention and control measures were implemented (P <0.05). Conclusion Mastering the drug resistance characteristics and distribution of MDRO, strengthening the supervision of prevention and control measures, and finding out the weak points in prevention and control are the keys to effectively prevent or reduce the MDRO nosocomial infection. The rational application of antimicrobial agents is the focus of the next target monitoring.