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目的通过对Ⅱ～Ⅲ期宫颈癌放疗后宫颈细针穿刺活检结果,探讨宫颈癌放疗剂量及疗效的临床意义。方法对23例放疗或同步放化疗的宫颈癌患者放疗A点剂量达70～75gy后,在宫颈原发病灶部位行细针穿刺活检,达PCR的患者停止放疗,未达PCR的患者继续放疗,放疗剂量增加至75～85gy。结果 23例患者治疗后病理结果达PCR的有15例,未达PCR的有8例,此8例患者继续给予后装近距离照射补量5～10gy后再次活检,病理达PCR。23例患者穿刺均未出现出血及感染等并发症。结论细针穿刺活检有操作简单易行,创伤小,并发症少,患者痛苦小易接受等优点,且获得的病理诊断对宫颈癌的治疗有重要的临床指导意义。
Objective To investigate the clinical significance of radiotherapy dose and efficacy of cervical cancer by examining the results of cervical fine needle aspiration biopsy after radiotherapy of stage Ⅱ ~ Ⅲ cervical cancer. Methods A total of 23 patients with cervical cancer undergoing radiotherapy or concurrent chemoradiotherapy were treated with A-point dose of 70-75 Gy. Fine-needle aspiration biopsy was performed on the primary lesion of the cervix. Patients who achieved PCR were stopped radiotherapy. Patients who did not achieve PCR were further treated with radiotherapy. Radiotherapy dose increased to 75 ~ 85gy. Results The pathological results of 23 patients after treatment were 15 cases of PCR, 8 cases of less than PCR, 8 cases of patients continue to be equipped with close range irradiation dose of 5 ~ 10gy after biopsy again, the pathology of PCR. Twenty-three patients had no complications such as bleeding and infection. Conclusion Fine-needle aspiration biopsy has the advantages of simple and easy operation, less trauma, less complications and less painful patient acceptance. The obtained pathological diagnosis has important clinical significance for the treatment of cervical cancer.