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54例OAD但血糖控制不良的老年T2DM患者(HbAlc>7.5%),随机分为甘精组(n=28)和预混组(n=26),分别采用每晚9点注射甘精加二甲双胍和预混素(诺和灵30R)早晚餐前皮下注射治3个月。结果治疗后两组空腹血糖(FBG)、餐后2小时血糖(2hPBG)和糖化血红蛋白(HbAlc)无明显差异(P>0.05)。但甘精组低血糖发生率明显少于预混组P<(0.05)。结论甘精联合二甲双胍可使更多的老年T2DM患者的血糖达标,减少低血糖事件发生。
Fifty-four elderly patients with OAD but poorly controlled glycemic control (HbAlc> 7.5%) were randomly divided into Gan Gan group (n = 28) and pre-mixed group (n = 26) And premixed prime (Novolin and 30R) subcutaneous injection of breakfast and dinner for 3 months. Results There was no significant difference in fasting blood glucose (FBG), 2hPBG and HbAlc between the two groups after treatment (P> 0.05). However, the incidence of hypoglycaemia in Gan Gan group was significantly less than that in the premixed group (P <0.05). Conclusions Gandeng combined with metformin can make more elderly patients with T2DM blood glucose compliance, reduce the incidence of hypoglycemic events.