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目的:测定阴道炎栓中甲硝唑的含量。方法:采用一阶导数光谱,以297nm 波长处测定。结果:一阶导数光谱振幅D值与甲硝唑的含量成线性关系,同时可排除栓剂中其它组分的干扰。测得平均回收率99-43 % ,RSD为0-42 % 。结论:本实验确定了阴道炎栓中甲硝唑的直接定量测定方法
Objective: To determine the content of metronidazole in vaginitis suppository. Methods: The first derivative spectra were taken at 297 nm wavelength. Results: The first-order derivative of the spectral amplitude D and the content of metronidazole linear relationship, while excluding the suppository interference of other components. The average recovery was measured 99-43% with RSD of 0-42%. Conclusion: This experiment determined the direct quantitative determination of metronidazole in vaginitis suppository