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本文报导的是Ames试验与玻璃电极配合组成的能对致突变物质进行微量、快速测定的微生物传感器。所需时间在11小时以内,是普通方法的1/4,测定阳性物质Dexon的最低浓度为0.05μg/ml;而Ames试验为50μg/ml。 1.原理鼠伤寒沙门氏菌TA98在致突变物质的作用下发生回复突变而能自行合成组氨酸,在
This article reports the Ames test and glass electrode composition of the mutagenic substances can be micro, rapid determination of microbial sensors. The time required is within 11 hours, which is 1/4 of the normal method. The lowest concentration of Dexon, which is the positive substance, is 0.05 μg / ml. The Ames test is 50 μg / ml. 1. The principle of Salmonella typhimurium TA98 in the mutagenic material under the action of a mutation that can self-histidine, in the