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手足口病是由肠道病毒引起的传染病,曾在多个国家引起爆发流行。重症手足口病可导致脑炎/脑膜炎,其起病急,发展快,病死率高;对其早期识别并干预,是降低病死率的关键。早期诊断脑炎/脑膜炎,脑脊液检查具有较强的及时性及可操作性。目前关于手足口病合并脑炎的脑脊液变化报道较少,更缺乏脑脊液的动态监测研究。本研究纳入42例重症手足口病合并脑炎患儿,观察其颅内压及脑脊液的变化,报告如下。
Hand, foot and mouth disease is an infectious disease caused by enteroviruses that has caused an outbreak in many countries. Severe hand, foot and mouth disease can lead to encephalitis / meningitis, the onset of acute, rapid development, high mortality; its early identification and intervention, is the key to reducing mortality. Early diagnosis of encephalitis / meningitis, cerebrospinal fluid examination has a strong timeliness and maneuverability. At present, there are few reports on cerebrospinal fluid changes in hand, foot and mouth disease with encephalitis, and lack of dynamic monitoring of cerebrospinal fluid. This study included 42 cases of severe HFMD in children with encephalitis, observation of intracranial pressure and cerebrospinal fluid changes, the report is as follows.