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目的探讨椎动脉优势与后循环血管供应部位脑梗死的相关性及其后循环脑梗死的危险因素分析。方法选取保定市第一医院住院治疗符合本研究标准的急性脑梗死患者。回顾性分析所收集患者的性别、年龄、高血压、糖尿病、高脂血症、高同型半胱氨酸血症、既往短暂性脑缺血发作(TIA)史等资料,研究后循环脑梗死患者与椎动脉优势的相关性,应用Logistic回归分析得出后循环脑梗死的独立危险因素。结果椎动脉优势是后循环脑梗死发生的危险因素,且椎动脉优势组中基底动脉(BA)分区及小脑后动脉(PICA)分区的梗死发生率明显高于对照组。椎动脉优势、高同型半胱氨酸血症、既往TIA史均是后循环脑梗死的独立危险因素。结论椎动脉优势患者更易发生后循环PICA区和BA供血区梗死。有效防治高同型半胱氨酸血症以及TIA发作,对改善后循环脑梗死复发可能具有一定意义。
Objective To investigate the correlation between superiority of vertebral artery and cerebral infarction in posterior circulation vascular supply and analysis of risk factors of posterior circulation cerebral infarction. Methods The hospital of Baoding First Hospital was selected to meet the criteria of this study for patients with acute cerebral infarction. Retrospective analysis of the collected patients with gender, age, hypertension, diabetes, hyperlipidemia, hyperhomocysteinemia, previous history of transient ischemic attack (TIA) and other data to study patients with recurrent cerebral infarction And the superiority of vertebral artery correlation, using Logistic regression analysis of independent risk factors for posterior circulation cerebral infarction. Results The superiority of vertebral artery was the risk factor of posterior circulation cerebral infarction. The incidence of infarction in basilar artery (BA) and posterior subclavian artery (PICA) in superior vertebral artery group was significantly higher than that in control group. Vertebral artery superiority, hyperhomocysteinemia, history of previous TIA are independent risk factors for posterior circulation cerebral infarction. Conclusions Patients with predominant vertebral artery are more likely to have recurrent PICA and BA infarction. Effective prevention and treatment of hyperhomocysteinemia and TIA seizures, to improve the recurrence of recurrent cerebral infarction may be of some significance.