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目的观察神经节苷脂(GM1)联合丹红注射液对急性脑梗死的治疗效果。方法急性脑梗死患者96例,将其随机分为联合治疗组48例,以神经节苷脂40mg+5%GS250ml静脉滴注,1次/d,共14d;合并丹红注射液20ml+5%GS250ml静脉滴注,1次/d,共14d。对照组48例,以丹红注射液20ml+5%GS250ml静脉滴注,1次/d,共14d。两组基础用药治疗相同。于治疗前、后对两组患者的神经功能缺损程度(NDS)及日常生活活动量(ADL)进行评分比较。结果治疗组在治疗前、后比较NDS评分及ADL评分差异有统计学意义(P<0.01);治疗组与对照组相比,NDS评分和ADL评分差异有统计学意义(P<0.05)。结论神经节苷脂(GM1)联合丹红注射液能更好地改善急性脑梗死患者的预后,降低患者的神经功能的缺损程度。
Objective To observe the therapeutic effect of ganglioside (GM1) combined with Danhong injection on acute cerebral infarction. Methods A total of 96 patients with acute cerebral infarction were randomly divided into combined treatment group (n = 48) and intravenous infusion of ganglioside (40mg + 5% GS250ml) once a day for 14 days. Combined with Danhong injection 20ml and 5% GS250ml intravenous infusion, 1 / d, a total of 14d. The control group of 48 cases, with Danhong injection 20ml +5% GS250ml intravenous infusion, 1 time / d, a total of 14d. Two groups of basic medication the same. Before and after treatment, the scores of neurological deficit (NDS) and daily living activity (ADL) were compared between two groups. Results There were significant differences in NDS score and ADL score before and after treatment in the treatment group (P <0.01). There was significant difference between the NDS score and the ADL score in the treatment group and the control group (P <0.05). Conclusion Ganglioside (GM1) combined with Danhong injection can better improve the prognosis of patients with acute cerebral infarction and reduce the degree of neurological deficits.