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1985年和1986年我国贵州省沿河县局部地区发生一种新的急性传染病——“纸坊”病流行,其病因是由肠道ECHO3型病毒引起。该病接触传染性很高,个别家庭全家患病,发病率和病死率高达12％和30％,为了寻找一种简单有效的血清学方法监测该病在沿河县其他乡村流行的可能性,我们于1987年用血凝抑制法调查了未曾发病地区村民ECHO3型病毒抗体,现将调查结果报告如下。
In 1985 and 1986, a new acute infectious disease called “paper mill” was endemic in a part of Yanhe County, Guizhou Province, China. The etiology of the disease was caused by the intestinal ECHO3 virus. The disease is contagious and the incidence of morbidity and mortality in individual families is as high as 12% and 30%. In order to find a simple and effective serological method to monitor the prevalence of the disease in other villages in Yanhe County, In 1987, we used the hemagglutination inhibition method to investigate the ECHO3 type antibody in villagers who had never been infected. The findings are as follows.