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目的 :探讨老年椎 -基底动脉供血不足 (VBI)性眩晕的病因。方法 :对比老年VBI(5 8例 )、椎 -基底动脉脑梗死 (34例 )和健康老年人 (4 0例 )的X线颈椎片异常率、TCD异常率和血流变学检测样本均数。结果 :X线颈椎片异常率三组间均无显著差异 (P >0 .0 5 )。TCD异常率VBI组大于健康老年组 ,二者有非常显著的差异 (P <0 .0 1) ,而VBI与椎 -基底动脉脑梗死组间无差异 (P >0 .0 5 )。血流变学检查中全血粘度 ,红细胞压积、纤维蛋白原在VBI组与健康老年组及VBI与椎 -基底动脉脑梗死组间均有显著差异 (P <0 .0 5 ) ,但红细胞聚集指数前者有显著性差异 (P <0 .0 5 ) ,后者无显著差异 (P >0 .0 5 )。结论 :高粘滞血症和脑动脉硬化是老年VBI发病的主要原因 ,防治高粘滞血症和动脉硬化对降低VBI发病率具有临床意义
Objective: To investigate the etiology of vertebrobasilar insufficiency (VBI) vertigo in elderly patients. Methods: The rates of X-ray cervical vertebral disc abnormalities, TCD abnormalities and hemorheology were compared between old VBI (58 cases), vertebro-basilar cerebral infarction (34 cases) and healthy elderly (40 cases) . Results: There was no significant difference in abnormal rate of X-ray cervical spine between three groups (P> 0.05). The abnormal rates of TCD in VBI group were significantly higher than those in healthy elderly group (P <0.01), but there was no significant difference between VBI group and vertebro-basilar cerebral infarction group (P> 0.05). Hemodynamic examination of whole blood viscosity, hematocrit, fibrinogen in VBI group and healthy elderly group and VBI and vertebrobasilar cerebral infarction group were significantly different (P <0. 05), but the red blood cells The former had significant difference (P <0.05), while the latter had no significant difference (P> 0.05). Conclusions: Hyperviscosity and cerebral arteriosclerosis are the main causes of the onset of VBI in the elderly. Prevention and treatment of hyperviscosity and arteriosclerosis have clinical significance in reducing the incidence of VBI