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目的探讨新生儿肺出血的临床特点。方法回顾性分析我院新生儿科2010年1月至2012年6月新生儿肺出血患儿的临床特点,总结肺出血患儿的胎龄、体重、原发病、血浆及呼吸机使用情况,以及治疗和转归。结果共41例新生儿肺出血患儿,胎龄<30周16例(39%),30～36周15例(36.5%);体重<1000g10例(24%),1000～1499g18例(44%)。肺出血发生率较高的原发因素主要有窒息、缺氧、肺透明膜病、肺部感染。共死亡9例,输血浆患儿26例,死亡4例;未输血浆患儿15例,死亡5例,差异有统计学意义(P<0.05)。常频机械通气29例,死亡6例;高频振荡通气12例,死亡3例,差异无统计学意义(P>0.05)。结论肺出血的发生与早产、低出生体重、窒息缺氧、肺透明膜病以及肺部感染有关,发生肺出血后应予全身综合治疗。
Objective To investigate the clinical features of neonatal pulmonary hemorrhage. Methods The clinical features of neonates with pulmonary hemorrhage from January 2010 to June 2012 in our hospital were analyzed retrospectively. The gestational age, weight, primary disease, plasma and ventilator usage in children with pulmonary hemorrhage were summarized. Treatment and outcome. Results A total of 41 neonates with pulmonary hemorrhage were included in this study. The gestational age was less than 30 weeks in 16 patients (39%), 30 to 36 weeks in 15 patients (36.5%), 10 patients (1000%), 1000 to 1499g in 18 patients ). Primary factors of higher incidence of pulmonary hemorrhage are asphyxia, hypoxia, hyaline membrane disease, lung infection. There were 9 deaths in total and 26 deaths in plasma. There were 4 deaths and 15 deaths without plasma in 5 patients. The difference was statistically significant (P <0.05). Frequent mechanical ventilation in 29 cases, 6 patients died; high-frequency oscillatory ventilation in 12 cases, 3 patients died, the difference was not statistically significant (P> 0.05). Conclusions The occurrence of pulmonary hemorrhage is related to premature birth, low birth weight, asphyxia and hypopnea, hyaline membrane disease and pulmonary infection. After systemic hemorrhage, systemic hemorrhage should be treated.