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对122例不育症睾丸活检标本进行观察分析。结果表明,病变累及的部位主要为曲细精管生精上皮(122/122),依次为曲细精管界膜(78/122)、睾丸间质(68/122)。病理组织学分类为生精细胞脱落管腔雍塞50例(40.9%),生精障碍26例(21.3%),生精功能低下18例(14.8%),生精细胞发育不全17例(14.0%).曲细精管透明变性7例(5.8%),克氏征3例(2.5%),混合病变1例。睾丸活检对男性不育症的诊断、分型、治疗及预后判断均具有重要价值。本文亦对精索静脉曲张致使不育进行了讨论。
122 cases of sterility testis biopsy specimens were observed and analyzed. The results showed that the lesions mainly involved the seminiferous epithelium (122/122), followed by the seminiferous tubule (78/122) and the testicular stroma (68/122). Histopathology was classified into 50 cases (40.9%) of spermatogenic cells extubation, 26 cases (21.3%) of spermatogenic disorders, 18 cases (14.8%) of spermatogenic dysfunction, spermatogenic cells Dysplasia in 17 cases (14.0%). 7 cases of seminiferous tubules degeneration (5.8%), Kirschner sign in 3 cases (2.5%), mixed lesions in 1 case. Testicular biopsy is of great value in the diagnosis, classification, treatment and prognosis of male infertility. This article also discusses varicocele-induced infertility.