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目的观察经鼻持续正压通气(N-CPAP)治疗新生儿呼吸衰竭的疗效。方法对2007年6月—2008年9月收治的48例新生儿呼吸衰竭使用N-CPAP疗效及转归进行分析。结果治疗有效35例,应用N-CPAP后R、HR、PCO2、PO2均有明显改善。比较N-CPAP成功组和失败组临床资料显示,其胎龄、体质量有明显差异。使用N-CPAP与未使用N-CPAP比较,病死率明显降低。结论N-CPAP治疗新生儿呼吸衰竭可有较好的效果,但对于胎龄<32周、低体质量儿使用N-CPAP应慎重。
Objective To observe the effect of nasal continuous positive pressure ventilation (N-CPAP) on neonatal respiratory failure. Methods The efficacy and outcome of N-CPAP in 48 neonates with respiratory failure from June 2007 to September 2008 were analyzed. Results The treatment was effective in 35 cases, and R, HR, PCO2 and PO2 were significantly improved after N-CPAP treatment. Comparing the clinical data of N-CPAP successful group and failure group, there were significant differences in gestational age and body weight. The mortality rate was significantly lower with N-CPAP compared with no use of N-CPAP. Conclusion N-CPAP treatment of neonatal respiratory failure may have a good effect, but for gestational age <32 weeks, low birth weight children with N-CPAP should be careful.