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目的:比较干预前后某医院抗菌药应用状况,评价抗菌药应用合理性。方法:以处方分析指标和药物利用频度为指标,对比抗菌药干预前(2007年4季度)后(2008年)用药情况。结果:2008年抗菌药处方数比例为19.81%,二联以上用药维持为30%左右,平均处方中抗菌药的品种为1.35左右;但抗菌药平均处方费用和抗菌药应用强度逐渐下降,医师用药剂量与标准之比趋向于1。主要使用的抗菌药品种趋于分级管理的要求。结论:2008年我院抗菌药的应用趋于合理。干预措施成效令人满意。
Objective: To compare the application status of antibacterials in a hospital before and after intervention and to evaluate the rationality of antibacterials. Methods: Based on the analysis of prescriptions and the frequency of drug use, the comparison of the medication before antimicrobial treatment (4Q 2007) (2008) was made. Results: In 2008, the proportion of prescriptions for antimicrobial agents was 19.81%. The dosage of antimicrobials was maintained at about 30% in 2008 and the average prescription was 1.35. However, the average prescription cost of antimicrobial agents and the strength of antimicrobial agents decreased gradually. The dose to standard ratio tends to 1. The main antibacterial drugs used tend to be classified management requirements. Conclusion: The application of antibacterials in our hospital in 2008 tends to be reasonable. The results of the intervention are satisfactory.