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本文将14只麻醉犬采用Harris氏法二期结扎左冠状动脉前降支(LAD),以心外膜实时记录心室晚电位(VLP)为标准,对比研究了体表和心外膜信号平均心电图(SA—ECG)检测VLP的价值。结果表明:(1)梗塞区心外膜SA—ECG显示的VLP与实时记录结果显著相关(r=0.84,P<0.05);(2)结扎LAD3小时内,体表SA—ECG的V.LP阳性率为71.4％(10/14),3～6天降至50％(6/12);(3)体表SA—ECG特异性较强(91.67％),而敏感性较差(66.67％);(4)初步确定犬SA—ECG的VLP阳性指标为D_(QRS)≥60ms、D_(40)≥20ms和V_(20)≤16μV。
In this study, 14 anesthetized dogs were subjected to second-stage ligation of left anterior descending coronary artery (LAD) by Harris’s method. Real-time epicardial (VLP) recording of epicardial late potentials (VLPs) was used as a standard to compare surface and epicardial signal- (SA-ECG) to measure the value of VLP. The results showed that: (1) The VLP displayed by epicardial SA-ECG in infarction area was significantly correlated with real-time recording results (r = 0.84, P <0.05); (2) The positive rate of SA-ECG was 71.4% (10/14) in 3 days and decreased to 50% (6/12) in 3-6 days. (3) The specificity of SA-ECG was 91.67% ); (4) The VLP positive index of canine SA-ECG preliminarily determined was: D_ (QRS) ≥60ms, D_ (40) ≥20ms and V_ (20) ≤16μV.