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目的了解产科剖宫产围术期预防用抗菌药物的情况,对比分析临床药师对产科合理使用抗菌药物的干预作用。方法收集临床药师参与前2012年1~3月手术病历130份,参与后2012年4月~6月手术病历142份,分析用药合理性。结果临床药师参与产科剖宫产围术期预防用抗菌药物使用后,其选药、用药时机、用法、剂量、用药方式趋于合理,用药时间大幅缩短。结论临床药师实施合理用药干预措施有效、可行,但仍存在选药不当、用药疗程偏长等问题;参与围术期预防用抗菌药物的监督作用仍需加强。
Objective To understand the situation of antibiotic prophylaxis during cesarean section in obstetrics and to compare the intervention effect of clinical pharmacists on the rational use of antibiotics in obstetrics. Methods A total of 130 surgical records were collected from clinical chemists participating in the first three months of 2012. A total of 142 surgical records were collected from April to June 2012 to analyze the rationality of medication. Results Clinical pharmacists involved in the prevention of perioperative prophylaxis of cesarean section with antibacterial drugs, the selection of drugs, medication timing, usage, dosage, mode of treatment tends to be reasonable, medication time significantly reduced. Conclusion Interventions of clinical pharmacists with rational drug use are effective and feasible, but there are still some problems such as improper drug selection and long course of treatment. The supervisory effect of antimicrobial agents for perioperative prophylaxis still needs to be strengthened.