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顺铂（ Ｃ Ｄ Ｄ Ｐ） 和阿霉素（ Ａ Ｄ Ｍ） 已越来越多地用于肝癌的局部灌注化疗或化疗栓塞（ 和碘化油及明胶绵联合） ，取得了比较满意的效果。为了比较两种药物的治疗效果，对我院１９８８ 年至１９９５ 年收治的５０２ 例原发性肝癌分别用顺铂治疗３７６ 例，阿霉素治疗１２６ 例。结果示：⑴顺铂治疗组：局部化疗１７１ 例，有效（ 完全缓解＋ 部分缓解）１４５ 例，平均生存期１２７ 月；化疗栓塞２０５ 例，肿瘤坏死率８８ ％ ，平均生存期２８５ 月；⑵阿霉素组：局部化疗６６ 例，有效４３ 例，平均生存期９５ 月；化疗栓塞６０ 例，肿瘤坏死率５５ ％ ，平均生存期２０５ 月。两组比较，顺铂治疗组明显优于阿霉素组（ Ｐ ＜ ００１） 。
Cisplatin (C D P) and Adriamycin (A D M) have been increasingly used in local infusion chemotherapy or chemoembolization of liver cancer (combined with iodized oil and gelatin sponge) and have achieved satisfactory results. . In order to compare the therapeutic effects of the two drugs, 502 cases of primary liver cancer treated in our hospital from 1988 to 1995 were treated with cisplatin in 376 cases and doxorubicin in 126 cases. Results: (1) Cisplatin treatment group: 171 cases of local chemotherapy, 145 cases of effective (complete remission and partial remission), and an average survival of 12 to 7 months; 205 cases of chemotherapy embolization, 88% of tumor necrosis, and an average survival period of 28 to 5 Month; (2) Adriamycin group: 66 cases were treated with local chemotherapy, 43 cases were effective, and the average survival period was 9 months and 5 months. Chemoembolization was performed in 60 cases. The tumor necrosis rate was 55%. The average survival period was 20 months. Compared with the two groups, the cisplatin treatment group was significantly better than the adriamycin group (P < 0 01).