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遗传不稳定性是一个概括性术语。它是许多物种细胞衰老的重要成分[1,2 ] 。它导致去调节基因表达 ,因而导致细胞生理年龄障碍 ,细胞生长停止和最终导致细胞死亡或它的母细胞转化。基因组依赖年龄不稳定性在细胞的生活中可以具有积极的意义。同时控制障碍可以导致肿瘤形成、突变
Genetic instability is a general term. It is an important component of cellular senescence in many species [1,2]. It leads to the regulation of gene expression, which leads to the age-limitation of the cell’s physiology, the cessation of cell growth and eventually cell death or its transformation of the blast cells. Genomic dependence on age instability can have a positive meaning in the life of cells. At the same time control disorders can lead to tumor formation and mutation