红厚壳叶中(口山)酮类成分

• 作 者: 李媛 李占林 刘明生 李丹毅 张慧 华会明
• 机 构: 沈阳药科大学中药学院,海南医学院,
• 出 处: 药学学报
• 发表日期: 2009年02期
• 关键词: 红厚壳属植物 红厚壳 叶中 化合物 醇提取物 (口山)酮 波谱数据分析 石油醚 氯仿萃取物 酚羟基质子信号

为了研究红厚壳叶中的(口山)酮类成分,采用多种色谱方法对红厚壳叶95%乙醇提取物进行分离纯化,从氯仿萃取物中分离得到1个新化合物inophyxanthone A(1)以及4个已知化合物pancixanthone A(2)、gerontoxanthone B(3)、jacareubin(4)和pyranojacareubin(5),其中化合物2为首次从该植物中分离得到,化合物3为首次从红厚壳属植物中分离得到。经波谱数据分析鉴定inophyxanthone A(1)的结构为1,3,5-三羟基-2-(1,1-二甲基-烯丙基)(口山)酮。

In order to study the ketone components in red thick leaves, a variety of chromatographic methods were used to separate and purify the 95% ethanol extracts of red thick leaves, and a new compound inophyxanthone A (1) was isolated from the chloroform extract. And 4 known compounds, pancixanthone A(2), gerontoxanthone B(3), jacareubin(4) and pyranojacareubin(5), of which compound 2 was isolated from the plant for the first time, and compound 3 was first isolated from the red thick shell. Plants were isolated. The structure of inophyxanthone A(1) was identified by spectral data analysis as 1,3,5-trihydroxy-2-(1,1-dimethyl-allyl)(oral) ketone.