8-bromo-7-methoxychrysin inhibits properties of liver cancer stem cells via downregulation of β-cate

• 作 者: Mei-Fang Quan Li-Hong Xiao Zhi
• 机 构: MedicalCollege,Departmentofpathology
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2013年43期
• 关键词: LIVER CANCER CANCER stem cell 8-bromo7-methoxychrysin SELF-RENEWAL Β-CATENIN Liv
• 基金项目: Supported by National Natural Science Foundation of China,No.81172375,Scientific Research Fund of Hunan Normal University,No.81105

AIM:To evaluate whether 8-bromo-7-methoxychrysin(BrMC),a synthetic analogue of chrysin,inhibits the properties of cancer stem cells derived from the human liver cancer MHCC97 cell line and to determine the potential mechanisms.METHODS:CD133+cells were sor