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目的探讨依达拉奉治疗急性脑梗死的疗效。方法我院神经内科2009-01～2009-09住院急性脑梗死患者90例,随机分为治疗组和对照组,治疗组采用0.9%氯化钠250ml+奥扎格雷钠80mg,2次/d,10～14d次一疗程,同时给予依达拉奉用法0.9%氯化钠100ml+依达拉奉30mg,bid,ivgtt,10d一疗程;对照组采用0.9%氯化钠250ml+奥扎格雷那80mg,2次/d,10～14d一疗程,2组同时给予脱水减轻脑水肿对症治疗。结果治疗组神经功能缺损程度有很大改善,总有效率97.33%;对照组用药一疗程,神经功能缺损改善差,总有效率77.33%。结论奥扎格雷钠联合依达拉奉治疗急性脑梗死疗效显著。
Objective To investigate the efficacy of edaravone in the treatment of acute cerebral infarction. Methods 90 cases of hospitalized patients with acute cerebral infarction from January 2009 to September 2009 were randomly divided into treatment group and control group. The treatment group was given 0.9% sodium chloride 250ml + ozagrel sodium 80mg twice daily, ~ 14d times a course of treatment, while the application of edaravone 0.9% sodium chloride 100ml + edaravone 30mg, bid, ivgtt, 10d a course of treatment; control group with 0.9% sodium chloride 250ml + ozagrel 80mg, twice / d, 10 ~ 14d a course of treatment, two groups were given dehydration to alleviate cerebral edema symptomatic treatment. Results The degree of neurological deficit in the treatment group was greatly improved, with a total effective rate of 97.33%. In the control group, the improvement of neurological deficit was poor with a course of treatment, with a total effective rate of 77.33%. Conclusion Ozagrel sodium combined with edaravone has significant therapeutic effect on acute cerebral infarction.