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蜂胶乙醇提取物(EEP)的抗肿瘤作用在患埃利希癌的成熟小鼠身上得到了证明。将EEP治疗过的小鼠的存活率与用争光霉素治疗过的进行比较,两天喂一次药,单独喂或两种药一起喂,先给药36天,追加观察14天,50天后用EEP治疗的存活率为55％,用争光霉素治疗的存活率为40％,用EEP和争光霉素混合物治疗的存活率小对于照组。争光霉素在细胞色素c还原酶存在时其在体内的活性降低,所以对EEP抗肿瘤作用的进一步研究很有意义。
The anti-tumor effect of propolis ethanol extract (EEP) has been demonstrated in mature mice with Ehrlichia carcinoma. The survival rate of EEP-treated mice was compared with those treated with bleomycin, and the drugs were fed once a day for two days and fed either alone or together. The first administration was 36 days, the additional observation was 14 days, and 50 days later. The survival rate of EEP treatment was 55%, the survival rate with bleomycin treatment was 40%, and the survival rate with EEP and bleomycin mixture treatment was small for the control group. In the presence of cytochrome c reductase, the activity of bleomycin is reduced in vivo, so further research on the anti-tumor effect of EEP is very meaningful.