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分化型甲状腺癌包括甲状腺乳头癌和滤泡癌,其中甲状腺滤泡癌生长缓慢,其发病率远低于甲状腺乳头癌,而且体积小、生长缓慢,常无明显的局部恶性表现。然而Do等~([1])研究发现甲状腺滤泡癌的骨转移发生率(6.8%)明显高于甲状腺乳头癌的骨转移发生率(0.4%)。临床上甲状腺滤泡癌骨转移的好发部位以肋骨、髂骨和胸骨多见,以溶骨性病变为主。骨转移会引发骨痛、病理性骨折和脊髓压迫等并发症,患者的生活质量将受到严重的影响~([2])。同时,甲状腺滤泡癌骨转移患者的10年生存率为13%~
Differentiated thyroid cancer, including thyroid papillary carcinoma and follicular carcinoma, thyroid follicular carcinoma of which growth is slow, the incidence is much lower than thyroid papillary carcinoma, and small, slow growth, often without significant local malignant performance. However, Do et al. ([1]) found that the incidence of bone metastases (6.8%) in thyroid follicular carcinoma was significantly higher than that of thyroid papillary carcinoma (0.4%). Clinical thyroid follicular carcinoma of the bone metastasis of the site of the ribs, iliac and sternal more common to osteolytic lesions based. Bone metastases can cause complications such as bone pain, pathologic fractures and spinal cord compression, and the quality of life of patients will be severely affected (2). At the same time, thyroid follicular carcinoma patients with bone metastases 10-year survival rate was 13% ~