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目的 :分析和探讨硝苯地平治疗先兆早产的临床效果。方法 :选择了我院在2015年1月-2015年6月收治的80例先兆早产患者作为研究对象,按照入院先后顺序将其随机分成观察组和与对照组,对照组患者给予硫酸镁常规治疗,而观察组患者给予了硝苯地平治疗,一段时间后对两组患者显效时间(即宫缩被抑制的时间)、延迟时间、妊娠结果以及不良反应发生情况进行记录和对比。结果 :观察组患者的显效时间(3.1±1.6)h明显低于对照组(4.7±2.2)h,并且观察组患者延长>7d、延长>35w的患者比例均高于对照组,他们之间的数据差异存在统计学意义(P<0.05)。而两组在延长≥2d的比例方面无明显差异,不具有统计学意义(P>0.05)。同时观察组中新生儿出现死亡、畸形、窒息以及不良反应等的比例均低于对照组,他们之间的数据差异存在统计学意义(P<0.05)。结论:在先兆早产患儿临床治疗过程中为其提供硝苯地平治疗,不仅可以有效提高患者的显效时间,而且还能改善新生儿的妊娠结果,降低不良反应的发生。
Objective: To analyze and discuss the clinical effect of nifedipine in the treatment of threatened preterm labor. Methods: Eighty patients with threatened preterm birth who were treated in our hospital from January 2015 to June 2015 were selected as study subjects. They were randomly divided into observation group and control group with conventional treatment of magnesium sulfate , While patients in the observation group were treated with nifedipine. After a period of time, the effective time (that is, the time when the contraction was inhibited), the delay time, the pregnancy results and the adverse reactions were recorded and compared. Results: The effective time (3.1 ± 1.6) h in the observation group was significantly lower than that in the control group (4.7 ± 2.2) h, and the proportion of patients in the observation group who were> 7 days and> 35 weeks were significantly higher than those in the control group Data differences were statistically significant (P <0.05). The two groups in the extension of ≥ 2d no significant difference in the proportion, not statistically significant (P> 0.05). At the same time, the proportion of neonatal death, malformation, asphyxia and adverse reactions in the observation group were lower than that of the control group, and there was significant difference between them (P <0.05). Conclusion: The treatment of nifedipine in children with threatened premature delivery can not only improve the effective time of the patients, but also improve the pregnancy outcome and reduce the incidence of adverse reactions.