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目的:研究经尿道前列腺钬激光剜除术(HoLEP)治疗BPH的疗效及安全性。方法:应用100 W钬激光和组织粉碎器对220例BPH患者行HoLEP及组织粉碎术,并分别记录患者术前、术中及术后随访的临床资料,分析及评估HoLEP的疗效及安全性。结果:220例手术均获成功,手术时间51~117(78.13±21.24)min,切除腺体58~144(82.47±19.25)g。术后留置导尿时间18~96(32.7±24.8)h,术后膀胱持续冲洗时间0~48(23.4±12.2)h,术后住院时间2~6(3.13±1.01)d,术后国际前列腺症状评分(IPSS)、生活质量(QOL)评分、最大尿流率(Qmax)、剩余尿量(RUV)较术前明显改善(P<0.01)。术后并发症发生率低。结论:HoLEP治疗BPH疗效安全可靠,并发症少,剜除彻底,并且适应范围广,有可能成为治疗BPH新的金标准。
Objective: To study the efficacy and safety of transurethral holmium laser excision (HoLEP) in the treatment of BPH. Methods: HoPE and tissue smash were performed in 220 BPH patients with 100 W holmium laser and tissue shredder. The clinical data of patients were recorded before operation, during operation and after operation. The curative effect and safety of HoLEP were analyzed and evaluated. RESULTS: All of the 220 operations were successful. The operative time ranged from 51 to 117 (78.13 ± 21.24) min, and the number of resected glands from 58 to 144 (82.47 ± 19.25) g. Postoperative urinary catheterization time was 18-96 months (32.7 ± 24.8) h, duration of postoperative bladder irrigation was 0-48 (23.4 ± 12.2) h, postoperative hospital stay was 2-6 (3.13 ± 1.01) days, postoperative international prostate The score of symptom score (IPSS), quality of life (QOL), Qmax and RUV were significantly improved (P <0.01). The incidence of postoperative complications is low. Conclusions: HoLEP is safe and reliable in the treatment of BPH, with fewer complications, complete eradication and wide range of adaptation, which may become the new gold standard for the treatment of BPH.