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目的探讨氟西汀联合多潘立酮治疗功能性消化不良伴抑郁症的疗效临床。方法将69例功能性消化不良伴抑郁症患者随机分为治疗组和对照组,对照组口服多潘立酮片,治疗组在对照组的基础上加服氟西汀,8周后,比较两组临床疗效和治疗前后HRSD评分和SDS评分。结果两组总有效率差异有统计学意义(p<0.05),治疗组治疗前后SDS评分与HRSD评分比较差异有统计学意义(p<0.05),治疗后两组SDS评分与HRSD评分比较差异有统计学意义(p<0.05)。结论氟西汀联合多潘立酮治疗功能性消化不良伴抑郁症患者具有较好的临床疗效。
Objective To investigate the efficacy of fluoxetine combined with domperidone in the treatment of functional dyspepsia with depression. Methods Sixty-nine patients with functional dyspepsia and depression were randomly divided into treatment group and control group. Domperidone tablets were given orally in the control group. Fluoxetine was added to the treatment group on the basis of the control group. After eight weeks, the clinical efficacy was compared HRSD scores and SDS scores before and after treatment. Results There was significant difference in total effective rate between the two groups (p <0.05). There was significant difference between SDS score and HRSD score before and after treatment in the treatment group (p <0.05). There was significant difference between the two groups in SDS score and HRSD score Statistical significance (p <0.05). Conclusion Fluoxetine combined with domperidone in patients with functional dyspepsia and depression has a good clinical efficacy.