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120例糖尿病肾病患者随机分为两组,对照组60例用西药(奥扎格雷钠氯化钠注射液、阿托伐他汀钙、缬沙坦)治疗,治疗组在对照组的基础上加用中药木丹颗粒冲剂。两组均以4周为一个疗程,观察FPG、2hPG和UAER。结果治疗4周后,FPG、2hPG和UAER均有不同程度的下降。UAER下降明显优于对照组。差异有非常显著性意义(P<0.01)。结论奥扎格雷钠、阿托伐他汀钙、缬沙坦加用木丹颗粒冲剂治疗糖尿病肾病能显著提高疗效,降低尿白蛋白排泄率。
120 patients with diabetic nephropathy were randomly divided into two groups, the control group of 60 patients with western medicine (sodium ozagrel sodium and sodium injection, atorvastatin calcium, valsartan) treatment group in the control group based on the use of Chinese medicine Dan granules granules. Both groups took 4 weeks as a course of treatment, observed FPG, 2hPG and UAER. Results 4 weeks after treatment, FPG, 2hPG and UAER decreased to some extent. UAER decreased significantly better than the control group. The difference was significant (P <0.01). Conclusion Ozagrel sodium, atorvastatin calcium, valsartan plus Mudan granules granules in diabetic nephropathy can significantly improve efficacy and reduce urinary albumin excretion rate.