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目的研究影响经蝶垂体腺瘤术后常见并发症的相关因素。方法回顾120例单鼻孔经蝶治疗的垂体腺瘤患者的临床资料,进行logistic回归分析。结果尿崩与患者性别、肿瘤切除程度相关,且差异显著(P<0.05);低钠血症与肿瘤最大直径相关,且差异显著(P<0.05);垂体功能低下与肿瘤最大直径、病理类型相关,且差异显著(P<0.05)。结论单鼻孔经蝶垂体瘤术后并发症发生是多因素作用的结果,临床工作者应正确、全面地认识这些因素的作用以便采取多种治疗措施降低垂体腺瘤的术后并发症发生。
Objective To study the influencing factors of postoperative complications of transsphenoidal pituitary adenoma. Methods The clinical data of 120 patients with pituitary adenoma treated by single nostril transsphenoidal approach were retrospectively analyzed by logistic regression. Results Diabetes insipidus was associated with gender and tumor resection, and the difference was significant (P <0.05). Hyponatremia was associated with the maximum tumor diameter (P <0.05). Pituitary dysfunction was associated with tumor diameter, pathological type Related, with significant difference (P <0.05). Conclusions The postoperative complications of single nosocomial pituitary tumor are the result of multiple factors. Clinicians should correctly and comprehensively understand the role of these factors in order to take various treatment measures to reduce the postoperative complications of pituitary adenoma.