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目的分析血糖控制水平对妊娠期糖尿病(GDM)孕妇妊娠结局的影响。方法回顾性分析120例妊娠期糖尿病孕妇的临床资料。其中,治疗后,血糖控制不良者48例(A组),空腹血糖(FBG)>5.6mmol/L或餐后-2-h血糖(2-hPG)>6.7mmol/L),血糖控制良好者72例(B组,FBG≤5.6mmol/L,2-hPG≤6.7mmol/L);另选无GDM产妇54例作为对照(C组)。比较三组的妊娠结局。结果 A组孕妇的妊娠期高血压疾病和剖宫产率高于B组(12.5%vs.1.39%和16.67%vs.4.17%)(P<0.05),而且早产儿、巨大儿、胎儿窘迫和新生儿窒息的比例也高于B组(14.58%vs.2.78%、18.75%vs.4.17%、16.67%vs.2.78%和22.92%vs.4.17%)(P<0.05)。B组的上述指标均与C组相仿(P>0.05)。结论 GDM孕妇血糖控制不良会导致妊娠期高血压疾病、剖宫产、胎儿发生早产儿、巨大儿、胎儿窘迫和新生儿窒息等并发症发生率增高,控制血糖对GDM孕妇具有重要意义。
Objective To analyze the effect of blood glucose control on the pregnancy outcome of pregnant women with gestational diabetes mellitus (GDM). Methods The clinical data of 120 pregnant women with gestational diabetes mellitus were retrospectively analyzed. Among them, 48 patients with poor glycemic control (group A), fasting blood glucose (FBG)> 5.6 mmol / L or postprandial 2-h blood glucose> 6.7 mmol / L after treatment had good glycemic control 72 cases (group B, FBG≤5.6mmol / L, 2-hPG≤6.7mmol / L); 54 other women without GDM as control group (C). Comparison of three groups of pregnancy outcomes. Results The pregnancy-induced hypertension and cesarean section rate in group A were significantly higher than those in group B (12.5% vs.1.39% vs 16.67% vs.4.17%, P <0.05), but also in preterm infants, macrosomia, fetal distress Neonatal asphyxia was also higher in group B than in group B (14.58% vs 2.78%, 18.75% vs 4.17%, 16.67% vs 2.78% and 22.92% vs 4.17%, respectively) (P <0.05). The above indexes in group B were similar to those in group C (P> 0.05). Conclusion The poor control of blood glucose in pregnant women with GDM may lead to hypertensive disorder complicating pregnancy. Cesarean section, fetus with premature fetus, macrosomia, fetal distress and neonatal asphyxia may increase the complication rate. It is of great significance to control blood glucose in pregnant women with GDM.