MicroRNA-124 slows down the progression of Huntington＇s disease by promoting neurogenesis in the str

• 作 者: Tian Liu Wooseok Im Inhee Mook
• 机 构: DepartmentofBiomedicalSciences,DepartmentofNeurology,DepartmentofBiochemistry,ProteinMetabolismMedic
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2015年5期
• 关键词: 亨廷顿病 神经调节 纹状体 过氧化物酶体增殖物激活受体 蛋白水平 转基因小鼠 尿嘧啶核苷 旋转试验 nerve regeneration microRNA-12
• 基金项目: This study was supported by a grant （A121911 and HI14C2348） of the Korean Health Technology R＆D Project, Ministry of Health ＆ Welfare, and National Research Foundation of Korea （NRF） （2011-0012728 and

Micro RNA-124 contributes to neurogenesis through regulating its targets,but its expression both in the brain of Huntington’s disease mouse models and patients is decreased.However,the effects of micro RNA-124 on the progression of Huntington’s disease ha