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作者总结急性粒细胞性白血病诱导缓解期及进行骨髓移植的患者共88例。均住在无菌隔离病房并进无菌饮食。按预防性抗生素用药种类的不同将其随机分为两组: Neocon组:共47人,口服新霉素每12小时500mg及粘菌素每12小时150万U。 TSN组:共41人,口服复方新诺明(TMP)160mg及新诺明(80mg)每12小时1次。另外,两组均于服用抗生素前48小时开始加用抗霉菌药物(制霉菌素50万U,每12小时及二性霉素B 200mg、每6小时)。当体温升高时(≥38.5℃,或≥38℃、4小时以上)予加用广谱抗生素(“治疗性
The authors summarize a total of 88 patients with acute myeloid leukemia-induced remission and bone marrow transplantation. All live in sterile isolation ward and into a sterile diet. According to the types of prophylactic antibiotics were randomly divided into two groups: Neocon group: a total of 47 people, oral neomycin 500mg every 12 hours and colistin every 12 hours 1.5 million U. TSN group: a total of 41 people, oral compound cotrimoxazole (TMP) 160mg and cotrimoxazole (80mg) once every 12 hours. In addition, antifungal agents (nystatin 500,000 U every 12 hours and amphotericin B 200 mg every 6 hours) were administered to both groups 48 hours prior to antibiotic treatment. When the body temperature increases (≥ 38.5 ℃, or ≥ 38 ℃, 4 hours or more) with broad-spectrum antibiotics ("therapeutic