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目的:探讨经带宁胶囊配合中药外用法对子宫内膜异位症腹腔镜术后患者进行巩固治疗的临床疗效。方法:将50例子宫内膜异位症腹腔镜术后患者随机分为2组,治疗组25例术后进行中药综合疗法(口服经带宁胶囊、中药灌肠及中药外敷),连续治疗3个月,对照组25例术后应用长效GnRHa治疗。3个月后对2组患者治疗前后痛经程度缓解,CA125、EMAb的变化,伴随症状(肛门坠痛、性交痛、经期延长、经量过多等)等情况进行比较。结果:治疗后2组患者痛经症状及伴随症状较治疗前明显改善,血清CA125水平及EMAb阳性率均显著下降(均P<0.05);2组间比较差异无统计学意义(P>0.05)。结论:经带宁配合中药外用与GnRHa皮下注射均可改善子宫内膜异位症症状及病理基础,但中药多途径联合疗法较GnRHa皮下注射费用低,且治疗期间没有任何不适感,如有生育要求的患者在完成治疗后即可备孕,免除患者由于等待产生的焦虑情绪。
Objective: To investigate the clinical effect of Ningxia capsule combined with external application of traditional Chinese medicine on patients with endometriosis after laparoscopic consolidation therapy. Methods: Fifty patients with endometriosis after laparoscopic surgery were randomly divided into two groups. 25 cases in the treatment group were treated with traditional Chinese medicine (oral administration of Zhaining capsule, traditional Chinese medicine enema and external application of traditional Chinese medicine) and continuous treatment of three Month, the control group of 25 patients with long-term use of GnRHa treatment. Three months later, the degree of dysmenorrhea, the changes of CA125 and EMAb in the two groups before and after treatment were compared with those with symptoms (anal ankle pain, painful sexual intercourse, prolonged menstrual period, overdose, etc.). Results: After treatment, the dysmenorrhea symptoms and accompanying symptoms in both groups were significantly improved compared with those before treatment. The levels of serum CA125 and EMAb were significantly decreased (all P <0.05). There was no significant difference between the two groups (P> 0.05). CONCLUSION: The combination of Nao Ning and GnRHa subcutaneously can improve the symptoms and pathological basis of endometriosis. However, multi-route combination therapy of traditional Chinese medicine is less costly than subcutaneous injection of GnRHa, and there is no discomfort during treatment. If there is childbirth The required patient can be pregnant after completing the treatment, relieving the patient of anxiety caused by waiting.