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目的:研究血清铁蛋白(SF)、血清铁(SI)与冠心病(CHD) 之间的关系以及SF、SI与CHD有关危险因素的相关关系。方法:测定43 例心肌梗塞(MI),44 例心绞痛(AP) 患者的SF、SI、血脂、血糖(BG)、血压、腰臀比(WHR) 、体重指数(BWI)水平,与40 例健康对照组进行分析。结果:AP组、MI组男、女、总体SF水平分别明显高于对照组(P< 0.05~0.001),但女性升高不如男性明显;SF水平与WHR、甘油三脂(TG)、低密度脂蛋白(LDL)呈正相关(r= 0.46,0.34,0.44),与高密度脂蛋白(HDL)呈负相关(r= - 0.33)。结论:体内SF增加是AP、MI的主要易发因素之一;SF水平受营养因素特别是某些脂代谢及腹部脂肪分布的影响
Objective: To study the relationship between serum ferritin (SF), serum iron (SI) and coronary heart disease (CHD) and the related risk factors of SF, SI and CHD. Methods: The levels of SF, SI, blood lipid, blood glucose (BG), blood pressure, WHR and BWI in 43 patients with myocardial infarction (MI) and 44 patients with angina pectoris Control group for analysis. Results: The levels of SF in males and females in AP group and MI group were significantly higher than those in control group (P <0.05-0.001), but their females were not significantly higher than those in males. SF levels were positively correlated with WHR, triglyceride ), And low density lipoprotein (LDL) (r = 0.46,0.34,0.44), but negatively correlated with high density lipoprotein (HDL) (r = - 0.33). CONCLUSIONS: Increased SF in vivo is one of the major risk factors for AP and MI. SF levels are affected by nutritional factors, especially certain lipid metabolism and abdominal fat distribution