论文部分内容阅读
目的：探讨临床应用沙星类药物导致的不良反应发生情况，为临床安全应用该类药物提供参考。方法：对我院128例沙星类药物不良反应患者临床资料进行回顾性分析，并对数据进行统计分析。结果：沙星类药物不良反应男性发生率(63.28%)明显高于女性发生率(36.72%)，差异具有统计学意义(P<0.05)；41~60岁是沙星类药物不良反应发生的主要年龄段(53.91%)，高于其他年龄段(P<0.05)；涉及药物以左氧氟沙星为主(占25.00%)，给药方式以静脉滴注为主(占85.16%)；不良反应临床表现主要以全身性(25.00%)、神经系统(21.87%)为主。结论：沙星类药物不良反应发生较多，临床表现多样，在临床应用时应充分掌握其适应证、禁忌证，选择适宜的给药途径，合理用药，并注意对可能发生的不良反应进行预防，降低不良反应的发生率。“,”objective: to study the clinical application effect of drugs lead to adverse reactions occur, provide reference for clinical safe application of these drugs. Methods:128 cases of the effect of drugs in our hospital adverse reaction in patients with clinical data were retrospectively analyzed, and the data were statisti-cally analyzed. Results:the effect of the male incidence of adverse drug reactions (63. 28%) was significantly higher incidence of women (36. 72%), statistically significant difference (P < 0. 05);41 ~ 60 years old is the effect of drug adverse reactions such as the main age group (53. 91%), higher than other age groups (P < 0. 05); Involving the drug is given priority to with levofloxacin (25. 00%), dosing method is given priority to with intravenous drip (85. 16%); Adverse clinical manifestations mainly systemic (25. 00%), nervous system (21. 87%). Conclusion: the effect of ?