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目的:探讨雾化吸入布地奈德联合特布他林治疗小儿哮喘急性发作期治疗效果及应用价值。方法:选择我院治疗小儿哮喘急性发作患儿106例作为研究对象,采取随机数字表法分为观察组和对照组,每组各535例,对照组采用西医常规抗炎、止咳化痰治疗,观察组在对照组基础上联合雾化吸入布地奈德和特布他林,观察两组临床疗效。结果:观察组治疗总有效率为92.45%,对照组治疗总有效率为75.47%,组间对比差异有统计学意义(P<0.05)。观察组治疗后用力肺活量(1.34±0.56)L,第1秒末用力呼气容积(2.34±0.79)L;对照组治疗后用力肺活量(1.13±0.34)L,第1秒末用力呼气容积(1.93±0.50)L,组间对比差异有统计学意义(P<0.05)。结论:雾化吸入布地奈德联合特布他林治疗小儿哮喘急性发作可以提高治疗效果,明显改善患者肺功能指标,缓解临床症状和体征,值得在临床上大力推广使用。
Objective: To investigate the therapeutic effect and application value of inhalation of budesonide combined with terbutaline in the treatment of acute exacerbation of pediatric asthma. Methods: One hundred and sixty children with acute asthma in our hospital were selected as the research object. The random number table was divided into observation group and control group, with 535 cases in each group. The control group was treated with conventional anti-inflammatory and cough-resolving phlegm therapy, In the observation group, budesonide and terbutaline were inhaled on the basis of the control group, and the clinical efficacy was observed. Results: The total effective rate of the observation group was 92.45%, while that of the control group was 75.47%. The difference between the two groups was statistically significant (P <0.05). The forced vital capacity (1.34 ± 0.56) L and the forced expiratory volume at the second second (2.34 ± 0.79) L in the observation group after treatment; the forced vital capacity (1.13 ± 0.34) L in the control group after treatment, forced expiratory volume at the second second 1.93 ± 0.50) L, the difference between the two groups was statistically significant (P <0.05). Conclusion: The inhalation of budesonide combined with terbutaline for the treatment of acute asthma in pediatric patients can improve the therapeutic effect, significantly improve the pulmonary function indexes and relieve the clinical symptoms and signs of the patients, which is worth to be popularized in clinic.