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9月3日,《自然》杂志在日本干细胞生物学家笹井芳树自杀辞世近一个月时发表讣文,纪念这位干细胞领域的先驱。本文作者阿图罗·阿尔瓦雷茨-比拉(Arturo Alvarez-Buylla),加州大学旧金山分校的神经外科教授,他曾在2008年至2014年与笹井芳树有过合作。他称笹井为解密胚胎信号的干细胞生物学家。一个受精卵——单细胞是如何生成无数的特化细胞,再组装成三维组织和功能器官的?这一基础性的谜题让一代又一代的胚胎学家为之着迷。利用创造性的培养条件,以及对于支配组织发育的一
On September 3, Nature published an obituary in commemoration of a pioneer in the field of stem cells, nearly a month after Japanese stem cell biologist Sakurai Yoshitari committed suicide. Author Arturo Alvarez-Buylla, professor of neurosurgery at the University of California, San Francisco, collaborates with Sakurai Yoshie in 2008-2014. He said that Sakurai is a Stem Cell Biologist who decipates embryonic signals. How a single fertilized egg, a single cell, generates countless specialized cells and reassembled into three-dimensional tissues and organs? This fundamental puzzle puzzled generations of embryologists. Using creative training conditions, as well as one that governs the development of the organization