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目的:研究吸入噻托溴铵治疗稳定期慢性阻塞性肺疾病(COPD)的治疗效果。方法:60例稳定期COPD患者随机分成2组,治疗组给予噻托溴铵吸入,对照组给予常规治疗,比较2组治疗前后肺功能、6min步行距离并评价临床症状积分。结果:与对照组比较,治疗组FEV1/FVC以及FEV1占预计值百分比明显增加,6min步行距离、临床症状明显改善(P<0.05或P<0.01)。结论:吸入噻托溴铵可有效改善肺功能并缓解临床症状。
Objective: To investigate the therapeutic effect of inhalation of tiotropium on patients with stable chronic obstructive pulmonary disease (COPD). Methods: Sixty patients with stable COPD were randomly divided into two groups. The treatment group was given tiotropium inhalation. The control group was given routine treatment. The pulmonary function, the walking distance of 6 minutes and the clinical symptom scores were compared between the two groups. Results: Compared with the control group, FEV1 / FVC and FEV1 accounted for a significant increase in the percentage of the predicted value in the treatment group. The clinical symptoms were significantly improved at the 6-minute walking distance (P <0.05 or P <0.01). Conclusion: Tiotropium inhalation can effectively improve lung function and relieve clinical symptoms.