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目的了解乡镇卫生院因呼吸道疾病住院的患者喹喏酮类药物的使用,以及其使用对肺结核患者诊断的影响;为将来的结核病防治工作提供可行性建议。方法从开展耐多药防治工作的一个市和未开展耐多药防治工作的2个市所辖的所有县区中,分别随机抽取一个乡镇,调查2013年上半年所有因呼吸道疾病住院患者的抗生素使用情况,及结核诊断情况。结果调查的759例患者中,左氧氟沙星的使用率为38.47%,开展耐药工作的市和未开展耐药工作的市,左氧氟沙星的使用率无显著性差异(P>0.05)。最终确诊的23例肺结核患者,其诊断延误时间的四分位数间距为18.05 d,住院期间使用头孢和使用左氧抗炎的患者诊断延误时间无统计学差异(P>0.05)。结论应加强乡镇卫生院喹喏酮类药物规范使用的管理,避免耐药结核病的产生。
Objective To understand the use of quinolones in patients hospitalized for respiratory diseases in township hospitals and the impact of their use on the diagnosis of tuberculosis patients and to provide feasible suggestions for future tuberculosis prevention and treatment work. Methods One township and one township was randomly selected from one city under the multi-drug prevention and control work and two counties under the jurisdiction of the two cities that did not carry out MDR prevention and control. All antibiotics inpatients with respiratory diseases in the first half of 2013 were investigated. Use, and tuberculosis diagnosis. Results Among the 759 patients surveyed, the levofloxacin utilization rate was 38.47%. There was no significant difference in the use rate of levofloxacin between cities with drug resistance and those without drug resistance (P> 0.05). The final diagnosis of 23 cases of tuberculosis patients, the diagnosis of delay time quartile spacing was 18.05 d, hospital use of cephalosporin and left anti-inflammatory patients with delayed diagnosis of no significant difference (P> 0.05). Conclusion The management of quinolone drugs in township health centers should be strengthened to avoid the emergence of drug-resistant tuberculosis.