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Recently, silicate diagenesis has been the focus of many studies because of its impact on porosity and permeability in sedimentary rocks. In the process of diagenetic evolution, the crystallization, cementation, and corrosion of zeolite (as a diagenetic mineral) have different effects on properties of Permian reservoirs in the study area. In the Permian sediments in the northwestern margin of the Junggar Basin, Zeolite minerals have formed during diagenesis in an open hydrologic system, related to the hydration of abundant volcanic glass. Chemical property of groundwater, pH of pore water, cation property and ratios have directly influenced the transformation among various zeolites and the dissolution of zeolite mineral. The main species of zeolite include analcime, heulandite, and laumontite. Transformations of these minerals during diagenesis are: volcanic glass→ clinoptilolite→analcime→heulandite→laumontite. Corrosion of analcime obviously improved reservoir quality. Extensive heulandite cementation developed and intensively reduced reservoir pore spaces. Early zeolite cementation protected pore structure against compaction and provided substance for late dissolution. The dissolution of analcime was closely related with the organic acid recharged by hydrocarbon source rocks and the NaHCO3 type formation water in the Permian, and was sensitive to permeability of rocks. Within the CaCl2 type formation water, heulandite and laumontite were hardly dissolved. In the study area, the belt with dissolved analcime is the area for the development of secondary pores and favorable reservoirs.