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成骨生长肽是具有促进成骨和刺激造血作用的多肽类生长因子,原肽由十四个氨基酸组成,碳端五肽是维持原肽全部活性的最短氨基酸序列。本文就成骨生长肽的生物学特征及构效关系进行综述。
Osteogenic growth peptide is a polypeptide growth factor that promotes osteogenesis and stimulates hematopoiesis. The pro-peptide consists of fourteen amino acids. The carbon-terminal pentapeptide is the shortest amino acid sequence that maintains the full activity of the pro-peptide. This article reviews the biological characteristics and the structure-activity relationship of osteogenic growth peptides.