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据 Circulation(1996,93:2135)载 Rector 等报道称,美国的一些研究人员提出精氨酸(arginine)对心衰患者有良效。在此项交叉研究中共纳入15例病人。患者接受精氨酸5.6~12.6mg/日或安慰剂,为时6周,然后交叉改换用药6周。结果表明,应用精氨酸可改善功能状态;也能明显改善外周血管功能。与安慰剂相比,用精氨酸者在运动时前臂血流明显多于基线值,它还能改善动脉顺应性。患者对精氨酸疗法能很好耐受。
According to Circulation (1996, 93: 2135) contained Rector and other reports, some researchers in the United States arginine (arginine) in patients with heart failure have good effect. A total of 15 patients were enrolled in this crossover study. Patients received arginine 5.6 to 12.6 mg / day or placebo for 6 weeks, then crossover for 6 weeks. The results show that the application of arginine can improve functional status; can also significantly improve peripheral vascular function. Compared with placebo, arginine in forearm blood flow was significantly more than the baseline value, it can also improve arterial compliance. Patients tolerate arginine well.