论文部分内容阅读
目的 :分析乳癌和肺癌骨转移的影响特点 ,探讨颅骨对称性放射性浓集的可能机理。方法 :对 772例乳癌和肺癌患者的 99m Tc- MDP全身骨显像结果进行回顾性分析 ,结果 :乳癌和肺癌骨显像阳性率分别为 46 .83 %和 70 .75 % ,总阳性率为 6 0 .49%。两者骨转移好发部位基本一致 ,依次为胸部、椎体、骨盆、肢体和颅骨。且以多发转移为主 ,占 84.80 %。全身骨显像发现颅骨对称性放射性浓集 1 6 0例 ,发生率女多于男 ,二者之比为 3 .75∶ 1。主要集中在 41岁以上中、老年患者 ,占 75 .6 3 %。结论 :乳癌和肺癌骨转移部位以中轴骨为主 ,广泛多发不规则的放射性核素异常浓聚灶为其影像特征。颅骨对称性放射性浓集以绝经期及绝经期后妇女多见 ,与癌症的种类及骨转移无关 ,主要与性激素紊乱所致的骨代谢改变有关
Objective: To analyze the characteristics of bone metastasis in breast cancer and lung cancer and to explore the possible mechanism of symmetrical radioactive skull accumulation. Methods: The results of 99m Tc-MDP whole body bone imaging in 772 breast and lung cancer patients were retrospectively analyzed. The positive rates of bone imaging in breast cancer and lung cancer were 46.83% and 70.75%, respectively. The total positive rate was 6 0 .49%. Bone metastasis of both sites are basically the same, followed by the chest, vertebral body, pelvis, limbs and skull. And to multiple transfer-based, accounting for 84.80%. Whole body bone imaging found that skull symmetry radioactive concentration of 160 cases, the incidence of female than male, the ratio of the two was 3.75: 1. Mainly in the 41-year-old middle-aged patients, accounting for 75.63%. CONCLUSIONS: The bone metastases of breast cancer and lung cancer mainly consist of the central axis bone, and the extensive and irregular distribution of abnormal radionuclide imaging features. Skull symmetry of radioactive concentration in menopausal and postmenopausal women more common, and the type of cancer and bone metastasis has nothing to do, mainly related to changes in bone metabolism caused by sex hormone disorders