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系统性红斑狼疮(SLE)是一种器官非特异性常见病,具有与高丙球蛋白血症有关的 B 细胞超反应特征。本文作者用酶免疫试验,对25例有肾脏受累的 SLE 患者的血清及肾活检组织洗脱物中抗 DNA,三硝基苯(TNP)、肌动蛋白、微管蛋白、肌浆球蛋白和白蛋白等6种抗原的抗体活性进行了检测。70份正常人血清作对照测定。结果发现,与正常人血清比较,这些狼疮性肾炎患者的血清中均含有高滴度的抗上述6种抗原的 IgA 类抗体和明显的
Systemic lupus erythematosus (SLE) is a nonspecific, common disease of organs characterized by B-cell hyperreactivity associated with hypergammasein. The authors used enzyme immunoassay to detect anti-DNA, trinitrobenzene (TNP), actin, tubulin, and sarcomeric protein in serum and renal biopsy tissues of 25 SLE patients with renal involvement and Antibodies such as albumin and other 6 antigens were detected. 70 normal serum as control. The results showed that compared with normal serum, these patients with lupus nephritis serum containing high titers of the above-mentioned six kinds of antigens IgA antibodies and significant