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目的探讨盆腔浆液性腺癌的卵巢形态特点及其在盆腔浆液性腺癌发生中的意义。方法对43例浆液性腺癌进行分析,其中包括31例卵巢癌与12例腹膜癌,观察卵巢的大体与镜下形态以及合并的病变。结果 43例浆液性腺癌均有卵巢受累,35例(81.4%)为双侧性,42例累及多个脏器。大体观察,卵巢癌组与腹膜癌组卵巢表面有乳头与粘连的比率分别为65.3%与95.2%,切面实性的比率分别为35.2%与81.2%。镜下见卵巢癌与腹膜癌卵巢表面受累的比率分别为22.8%与66.7%,可见残存正常卵巢的比率为66.7%与100%。43例中6例合并子宫浆膜或卵巢子宫内膜异位,1例对侧卵巢考虑子宫内膜异位恶变,2例卵巢包涵腺体未见腺上皮的增生性改变。结论卵巢癌可能是盆腔浆液性腺癌多脏器受累的表现之一,卵巢癌与腹膜癌的卵巢存在很多相似与重叠形态,提示至少部分卵巢癌与腹膜癌有相似的来源,可能为继发性肿瘤。
Objective To investigate the ovarian morphological characteristics of pelvic serous adenocarcinoma and its significance in the occurrence of pelvic serous adenocarcinoma. Methods Seventy-three cases of serous adenocarcinoma were analyzed, including 31 cases of ovarian cancer and 12 cases of peritoneal carcinoma. The ovarian gross and microscopic morphology and the combined lesions were observed. Results All 43 cases of serous adenocarcinoma had ovarian involvement, 35 cases (81.4%) were bilateral and 42 cases involved multiple organs. In general, the ovarian and peritoneal ovarian cancer group had a ratio of 65.3% and 95.2% of the ovarian surface, respectively, and the ratio of solidified section was 35.2% and 81.2% respectively. Microscopic see the ovarian cancer and peritoneal ovarian surface involvement rates were 22.8% and 66.7%, showing that the proportion of residual normal ovary 66.7% and 100%. Among the 43 cases, 6 cases had uterine serosal or ovarian endometriosis, 1 case contralateral ovary considered endometriosis malignancy, and 2 cases did not show glandular epithelial hyperplastic changes in the ovary. Conclusions Ovarian cancer may be one of the manifestations of multiple organ involvement in pelvic serous adenocarcinoma. There are many similar and overlapping forms of ovary in ovarian and peritoneal carcinomas, suggesting that at least part of ovarian and peritoneal carcinomas have similar origin, which may be secondary Tumor.