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目的:观察肯特令联合庆大霉素治疗小儿秋季腹泻的疗效。方法:80例患儿随机分为两组,治疗组40例(男26例,女14例,年龄3个月～6岁)用肯特令加庆大霉素治疗。对照组40例(男21例,女19例,年龄4个月～6岁)用庆大霉素治疗。肯特令剂量为:<1岁者1.5g一天2次;1～2岁者1.5g一天3次;>2岁者每次3g,一天3次。加温水50ml空腹口服,疗程3天。庆大霉素剂量为:浓度为1.8％溶液,按10mg/(kg·d)一天3次口服,疗程3天。结果:治疗组总有效率为95.0％,对照组为62.5％。两组比较有非常显著差异(P<0.01)。治疗组不良反应小。结论:肯特令治疗小儿秋季腹泻可防止脱水,缩短病程。联合用药弥补了单用庆大霉素治疗的不足,可提高疗效。
Objective: To observe the curative effect of combination of gentamycin and gentamycin on children with autumn diarrhea. Methods: Eighty children were randomly divided into two groups. Forty patients (26 males and 14 females, aged 3 months to 6 years) in the treatment group were treated with keratin plus gentamicin. Control group of 40 patients (21 males and 19 females, aged 4 months to 6 years) with gentamicin treatment. Kent dose: <1 year old 1.5g twice a day; 1 to 2 years old 1.5g 3 times a day;> 2-year-old each 3g, 3 times a day. Warm water 50ml fasting oral medication, 3 days. Gentamicin dose: a concentration of 1.8% solution, according to 10mg / (kg · d) three times a day orally for 3 days. Results: The total effective rate was 95.0% in the treatment group and 62.5% in the control group. There was a significant difference between the two groups (P <0.01). Adverse reactions in treatment group was small. Conclusion: Kent Decoction treatment of children with autumn diarrhea can prevent dehydration, shorten the course. Combination therapy to make up for the lack of treatment with gentamicin alone can improve the efficacy.